Infinium QC array

Infinium QC Array-24 Kit

High-throughput, cost-effective genotyping microarray for quality control, tracking, and stratification applications, including biobanking.

5,760 samples per week

Sample throughput

24 samples per array

Number of samples

Fixed markers: 15,949.  Custom marker add-on capacity: None. 

Number of markers

See full details in the specifications table

Overview

The Infinium QC Array-24 Kit is a cost-effective way to perform sample identity, data interpretation1, and quality validation for high-throughput genomics, biobanking, and other applications requiring confirmation of sample identification and quality. The Infinium QC Array-24 Kit offers 15,949 markers focused on high-value functional content.

Key markers include:

  • Sex determination

  • Ethnic ancestry

  • ADME (absorption, distribution, metabolism, and excretion)

  • Linkage analysis

The Infinium QC Array-24 Kit uses the Infinium 24-sample high-throughput screening (HTS) format. When used with Illumina array scanners, the Infinium QC Array-24 Kit enables the high accuracy and high-throughput genotyping required for quality control, tracking, and stratification applications.

View manifest (array content) files

Specifications

Assay type Infinium HTS
Automation capability Liquid Handling Robots, Automated Array Loader
Description

This BeadChip consists of 15,949 markers focused on ADME, ethnic ancestry, linkage, and other categories that support sample tracking, quality control, and stratification for high-throughput genomics, biobanking, and other applications that require validation of sample identity and quality.
Input quantity 200 ng DNA
Instruments iScan System
Method Targeted Genotyping Array, High-Throughput Genotyping Array
Nucleic acid type DNA
Number of markers

Fixed markers: 15,949.  Custom marker add-on capacity: None. 
Number of samples 24 samples per array
Sample throughput 5,760 samples per week
Specialized sample types FFPE Tissue
Species category Human
Technology Microarray
Variant class Single nucleotide polymorphisms (SNPs), Germline variants, Structural variants, Insertions-deletions (indels), Copy number variants (CNVs)

Required products

Match kit size to the number of samples in a run. Each kit is processed as a single batch and is not designed to be divided across multiple experiments. Order multiple small kits if processing several low-throughput batches.

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Applications

The Infinium QC Array-24 Kit supports 15,949 markers focused on high-value functional content, including sex determination, ethnicity, and linkage analysis, that enables cost-effective and high-throughput genotyping required for quality control, tracking, and stratification applications.

Example workflow

1
Select microarray

Infinium QC Array-24 Kit

2
Scan
iScan System
3
Analyze
GenomeStudio Software

Related applications and methods

Microarray data analysis and experimental design

Find microarray data analysis tools and tips to help you to visualize and analyze microarray data and facilitate data analysis for large experiments.

High-throughput genotyping

Large-scale genotyping with microarrays can identify variants associated with disease risk in large cohorts or populations.

Human genotyping

Human genotyping arrays are ideal for processing thousands of samples to identify variants associated with traits and disease.

Documentation

Product literature
Support documentation

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Figures

Marker Category Number of Markers
ADME 1009
Ancestry Informative 2910
Blood Group 1659
FingerprintSNPs 477
Linkage 5486
Extended MHC 930
Mitochondrial 141
Sex Chromosomes X
1840		 Y
1401		 PAR
535

Infinium QC Array-24 v1.0 Kit marker information

The Infinium QC Array-24 v1.0 Kit offers markers focused on sex determination, ethnic ancestry, linkage, and several other categories.

Infinium QC Array-24 v1.0 Kit (48 samples)

20004347

The Infinium QC-Array-24 combines linkage, ancestry, sex determination, and functional markers to create a low cost, high throughput method for performing sample QC, tracking, validation, and stratification. Each Kit contains 2 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 48 DNA samples

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Infinium QC Array-24 v1.0 Kit (288 samples)

20004348

The Infinium QC-Array-24 combines linkage, ancestry, sex determination, and functional markers to create a low cost, high throughput method for performing sample QC, tracking, validation, and stratification. Each Kit contains 12 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 288 DNA samples

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Infinium QC Array-24 v1.0 Kit (1152 samples)

20004349

The Infinium QC-Array-24 combines linkage, ancestry, sex determination, and functional markers to create a low cost, high throughput method for performing sample QC, tracking, validation, and stratification. Each Kit contains 48 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 1152 DNA samples

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References

1. Ponomarenko P, Ryutov A, Maglinte DT, Baranova A, Tatarinova TV, Gai X. Clinical utility of the low-density Infinium QC genotyping array in a genomics-based diagnostics laboratory. BMC Med Genomics. 2017;10(1). doi:10.1186/s12920-017-0297-7.

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