As genomics-focused pharmacology begins to play a greater role in cancer treatment, next-generation sequencing (NGS) is emerging as a valuable method for obtaining a deeper and more accurate look into the molecular underpinnings of individual tumors. With targeted therapies becoming the new standard of care in oncology, NGS-driven companion diagnostics are widely seen as driving the selection of treatments to optimize patient outcomes in the future.
Compared to traditional methods, NGS offers advantages in accuracy, sensitivity, and speed that can make a significant impact on the field of oncology in the future. Because NGS can assess multiple genes in a single assay, it eliminates the need to order multiple tests to identify the causative mutation.
This multigene approach decreases the time to answer, providing a more economical solution and reducing the risk of exhausting precious clinical samples. In addition, NGS can provide high sensitivity, enabling the detection of mutations present at as little as 5% of the DNA isolated from a tumor sample.
NGS has the potential to change the future of oncology and advance the promise of personalized medicine. We invite you to learn more by examining the resources collected here.
By: Dr. Phil Febbo, Chief Medical Officer at IlluminaRead Article
Key opinion leaders discuss the ongoing challenges and potential of NGS in oncology testing.Read Interview
Provides customers the capability to run blood and tissue samples on the NovaSeq 6000 Sequencing SystemRead Article