Long-read sequencing is a highly accurate approach that can be used to:
Illumina Complete Long-Read technology (previously announced as “Infinity”) will power a novel, high-performance assay using standard next-generation sequencing (NGS) workflows and trusted Illumina sequencing by synthesis (SBS) chemistry.
The Illumina Complete Long-Read assay:
Stay up to date on Illumina Complete Long-Read products.
Illumina Complete Long-Read Prep, Human (launching in Q1 2023) is designed for human whole-genome sequencing (WGS). It provides a streamlined, integrated workflow compatible with all NovaSeq systems. This high-performance assay enables Illumina customers to generate thousands of highly accurate long-read genomes per year.
In addition to the whole-genome assay, Illumina long-read technology is compatible with enrichment. Targeted solutions focus on regions known to benefit from additional insight with longer reads. Future Illumina Complete Long-Read products with enrichment can create additional flexibility and scalability for human WGS and other applications.
See how Illumina long-read data can improve alignment and variant calling in traditionally challenging regions like repetitive regions, highly polymorphic regions, pseudogenes and paralogs, large indels, and structural variants.
Long-read sequencing technology has the potential to improve the efficiency and accuracy of many existing DNA sequencing applications while increasing the coverage of clinically important genes.
These advantages allow for the phased re‐sequencing of human genomes and rapid de novo sequencing of plant and animal genomes.
TELL-Seq technology generates ultra-long phasing blocks, providing an accessible solution to perform genome phasing studies.
TELL-Seq demonstrates exceptional performance for microbial WGS, even for challenging samples or regions with high GC content.
Researchers use transposase enzyme-linked long-read sequencing (TELL-Seq) to sequence and assemble genomes of nine insect species.
Understanding the variants associated with rare diseases can help researchers pinpoint the causes of genetic disorders.
Get a comprehensive base-by-base view of the unique genomic abnormalities in cancer.
Sequencing can help identify novel species, improve our food supply, and ensure a sustainable environment.