TruSight Myeloid Sequencing Panel

The TruSight Myeloid Sequencing Panel uses expert-defined content and proven next-generation sequencing (NGS) technology to identify somatic mutations in myeloid malignancies.

The panel content was designed by a consortium of recognized experts in blood cancer disorders and targets genes frequently mutated in:

  • Acute myeloid leukemia (AML)
  • Myelodysplastic syndrome (MDS)
  • Myeloproliferative neoplasms (MPN)
  • Chronic myelogenous leukemia (CML)
  • Chronic myelomonocytic leukemia (CMML)
  • Juvenile myelomonocytic leukemia (JMML)

The TruSight Myeloid Sequencing Panel (96 samples) covers 15 full genes (exons only) and 39 additional genes where oncogenic hotspots are covered, providing a comprehensive assessment of the key genes involved in myeloid malignancies in a single test. The result is an accurate, cost-effective solution for profiling liquid tumors. View the gene list »

TruSight Myeloid libraries are ideally suited to run on a desktop sequencer and perform alignment and variant calling with the Somatic Variant Caller. Filtering and annotation can then be performed using Illumina’s annotation and filtering software, VariantStudio.

ABL1 CEBPA HRAS MYD88 SF3B1
ASXL1 CSF3R IDH1 NOTCH1 SMC1A
ATRX CUX1 IDH2 NPM1 SMC3
BCOR DNMT3A IKZF1 NRAS SRSF2
BCORL1 ETV6/TEL JAK2 PDGFRA STAG2
BRAF EZH2 JAK3 PHF6 TET2
CALR FBXW7 KDM6A PTEN TP53
CBL FLT3 KIT PTPN11 U2AF1
CBLB GATA1 KRAS RAD21 WT1
CBLC GATA2 MLL RUNX1 ZRSR2
CDKN2A GNAS MPL SETBP1  

Product Literature

Description Document Type File Info
TruSight Myeloid Sequencing Panel Data Sheet PDF(< 1 MB)

Catalog IDs: FC-130-1010, FC-130-1003, FC-130-1006, FC-130-1007, MS-102-3003