Infinium OncoArray-500K Kit

The Infinium OncoArray-500K Kit is the most comprehensive, highest-density BeadChip available for researching cancer predisposition and risk. The Infinium OncoArray-500K contains 500,000 SNPs with a genome-wide backbone of 250,000 tag SNPs. Additional SNPs include genetic variants associated with breast, colorectal, lung, ovarian, and prostate cancers plus SNPs covering ancestry, quantitative traits, pharmacogenetics, and fine-mapping of common cancer susceptibility loci. To support additional research requirements, the Infinium OncoArray-500K can be tailored to incorporate up to 120,000 custom beadtypes*.

The Infinium OncoArray-500K was developed in collaboration with leading experts from the OncoArray consortium, and draws on many of the features of the successful Collaborative Oncological Gene-environment Study (iCOGS) array1. Designed with candidate SNPs identified by the consortium, the OncoArray provides the most cost-effective means to assess candidate variants potentially associated with cancer risk.

The Infinium OncoArray-500K uses a 24-sample high-throughput screening (HTS) BeadChip to enable maximum throughput, productivity, and genotyping accuracy. Using the proven iScan or HiScan Systems, the Infinium OncoArray-500K is designed to combine affordability with high-density content, providing insight into the relationship between gene variants and cancer predisposition in five of the most prevalent cancers.

* For additional information about custom add-on content, contact your Illumina account manager or sales specialist.
The OncoArray consortium is an international collaboration of leading experts from the NCI-supported Genetic Association and Mechanisms in Oncology (GAME-ON) consortium, Genome Canada, Genome Quebec, and Cancer Research UK.

 

References

1.       www.nature.com/icogs/primer/cogs-project-and-design-of-the-icogs-array

Product Literature

Description Document Type File Info
Infinium OncoArray-500K BeadChip Data Sheet PDF(< 1 MB)

Catalog IDs: WG-355-1001, WG-355-1002, WG-355-1003, WG-355-1011, WG-355-1012, WG-355-1013