A powerful, cost-effective genotyping microarray for large-scale genetic studies and pharmacogenomics in East Asian populations.
Sample throughput
Number of samples
Number of markers
The Infinium Asian Screening Array Kit contains 24-sample BeadChips plus reagents for population genetic studies in East and Southeast Asian populations.
This microarray was designed in collaboration with leading institutions. Content includes a genome-wide backbone using clinical research variants, QC markers, a discovery panel, and custom add-on content.
This microarray builds on the commercial success of the Infinium Global Screening Array. > 20M samples of Illumina Infinium arrays have been ordered by a global community of users.
Genotyping and CNV calling are supported for multiple sample types (eg, saliva, blood, buccal swabs, and FFPE samples). The high-throughput workflow maximizes sample processing while minimizing costs, instrumentation, lab space, and hands-on time.
Predesigned booster content is available as an optional add-on.
| Assay type | Infinium HTS |
|---|---|
| Automation capability | Liquid handling robots, Automated array loader |
| Description | Advanced genotyping array that provides a high-value, scalable, and cost-effective solution for population-scale genetic studies, variant screening, and precision medicine research in East and Southeast Asian populations. |
| Input quantity | 200 ng gDNA |
| Instruments | iScan System |
| Method | High-throughput genotyping array, Genome-wide genotyping array |
| Nucleic acid type | DNA |
| Number of markers | Fixed markers: ~ 660,000, Custom marker add-on capacity up to 50,000 |
| Number of samples | 24 samples per array |
| Sample throughput | ~2304 samples per week (estimate assumes 1 iScan System, 1 AutoLoader, 2 Tecan robots, and a 5-day work week) |
| Specialized sample types | Blood, FFPE tissue |
| Species category | Human |
| Technology | Microarray |
| Variant class | Single nucleotide polymorphisms (SNPs), Structural variants, Insertions-deletions (indels), Copy number variants (CNVs) |
Match your chosen kit size to the number of samples you run at a time. Each kit is processed as a single batch and is not designed to be divided across multiple experiments. If you are processing several low-throughput batches, order multiple small kits.
You can choose to customize your content using DesignStudio or select from a list of add-on content available as consortia boosters. Booster add-on content is available for multi-disease markers (~50K SNPs).
Check with your sales rep to confirm availability and pricing.
The Infinium FFPE QC Kit and Infinium HD FFPE DNA Restore Kit are optional but recommended when using the Infinium Asian Screening Array with formalin-fixed, paraffin-embedded (FFPE) samples.
The Infinium Asian Screening Array-24 v1.0 BeadChip enables cost-effective, scalable genomic screening of East Asian populations for a broad range of clinical research and variant screening applications, including disease association and risk profiling studies, pharmacogenomics research, disease characterization, lifestyle and wellness characterization, and marker discovery in complex disease.
Large-scale genotyping with microarrays can identify variants associated with disease risk in large cohorts or populations.
Human genotyping arrays are ideal for processing thousands of samples to identify variants associated with traits and disease.
Complex and genetic disease research
Comprehensive array and next-generation sequencing (NGS) solutions can accelerate research of various genetic complex diseases.
| Infinium Asian Screening Array-24 Kit | Infinium Global Screening Array-24 Kit | Infinium Global Diversity Array-8 Kit | |||
|---|---|---|---|---|---|
| Assay type | Infinium HTS | Infinium HTS | Infinium LCG | ||
| Automation capability | Liquid handling robots, Automated array loader | Liquid handling robots, Automated array loader | Liquid handling robots, Automated array loader | ||
| Description | Advanced genotyping array that provides a high-value, scalable, and cost-effective solution for population-scale genetic studies, variant screening, and precision medicine research in East and Southeast Asian populations. | The Infinium Global Screening Array Kit is an economical genotyping array for population-scale genetics, translational research, variant screening studies, and precision medicine research, combining optimized multiethnic genome-wide content, curated clinical research variants, and QC markers. | The 8-sample Infinium Diversity Array provides targeted coverage of more than 4800 key genes across the genome. Approximately 1.8M markers are included on the BeadChip for high exonic coverage in regions of disease relevance, providing highly accurate copy number variation calls, and an average resolution of 1.5Mb. | ||
| Input quantity | 200 ng gDNA | 200 ng | 200 ng DNA | ||
| Instruments | iScan System | iScan System | iScan System | ||
| Method | High-throughput genotyping array, Genome-wide genotyping array | High-throughput genotyping array, Genome-wide genotyping array | Genome-wide genotyping array | ||
| Nucleic acid type | DNA | DNA | DNA | ||
| Number of markers | Fixed markers: ~ 660,000, Custom marker add-on capacity up to 50,000 | 654,027 fixed markers. Custom marker add-on capacity: Up to 100K. | 1,825,277 fixed markers. Custom marker add-on capacity: Up to 175K. | ||
| Number of samples | 24 samples per array | 24 samples per array | 8 samples per array | ||
| Sample throughput | ~2304 samples per week (estimate assumes 1 iScan System, 1 AutoLoader, 2 Tecan robots, and a 5-day work week) | ~5760 samples per week | ~1728 samples per week | ||
| Specialized sample types | Blood, FFPE tissue | Blood, FFPE tissue, Buccal swabs, Saliva | Blood, FFPE tissue, Buccal swabs, Saliva | ||
| Species category | Human | Human | Human | ||
| Technology | Microarray | Microarray | Microarray | ||
| Variant class | Single nucleotide polymorphisms (SNPs), Structural variants, Insertions-deletions (indels), Copy number variants (CNVs) | Single nucleotide polymorphisms (SNPs), Structural variants, Copy number variants (CNVs) | Single nucleotide polymorphisms (SNPs), Loss of heterozygosity (LOH), Chromosomal abnormalities, Structural variants, Copy number variants (CNVs) |
Library Prep & Array Kit Selector
Find the right sequencing library preparation kit or microarray for your needs. Filter by method, species, and more. Compare, share, and order kits.
Identify sequencing panels or microarrays that target your gene(s) of interest.
DesignStudio Custom Assay Design Tool
DesignStudio is a web-based assay design tool to help researchers design and order custom genotyping microarray probes or custom sequencing assays.
Content was expertly selected from scientifically recognized databases to create a highly informative array for clinical research applications. Variant counts are current as of August 2018 and may be subject to change.
Clinical research content features an extensive list of pharmacogenomics markers selected based on CPIC1 guidelines and the PharmGKB2 database. Markers are arranged according to level of evidence as defined by the PharmGKB database. VIP, very important pharmacogene.
Whole-genome sequencing data used to build the Infinium Asian Screening Array-24 v1.0 BeadChip include Korean, Mongolian, and Malaysian samples currently not represented in publicly available reference populations.
| Population | Abbreviation | Cohort | Sequence Depth |
| Chinese | CHS-GIS | Genomics Institute of Singapore | 30× |
| Southern Han Chinese | CHS | 1000G - Southern Han Chinese | 2–4× |
| Chinese Dai | CDX | 1000G - Chinese Dai in Xishuangbanna | 2–4× |
| Han Chinese | CBD | 1000G - Bejing | 2–4× |
| Japanese | R-JAP1 | RIKEN W13 | 15× |
| Japanese | R-JAP2 | RIKEN W1–6 | 30× |
| Japanese | R-JAP3 | RIKEN W18 | >30× |
| Japanese | K-JAP | KYOTO | 3–15× |
| Japanese | JAP | 1000G - Tokyo | 2–4× |
| Korean | M-KOR | MACROGEN | 15–30× |
| Korean | KPGP | The Personal Genome Project Korea (KPGP) | ~35× |
| Malaysian | MAL | Singapore Population Health Study | 30× |
| Mongolian | MON | MACROGEN | 30× |
| Vietnamese | KVT | 1000G - Kinh in Ho Chi Minh | >2–4× |
Clinical Pharmacogenetics Implementation Consortium (CPIC). cpicpgx.org. Accessed October 2016.
PharmGKB, The Pharmacogenomics Knowledgebase. www.pharmgkb.org. Accessed January 2017.
Infinium Asian Screening Array-24 v1.0 Kit (48 samples)
20016317
The Asian Screening Array is a universal, whole genome array for highly economical genetic risk screening. Each Kit contains 2 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 48 DNA samples.
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Infinium Asian Screening Array-24 v1.0 Kit (288 samples)
20016318
The Asian Screening Array is a universal, whole genome array for highly economical genetic risk screening. Each Kit contains 12 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 288 DNA samples.
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Infinium Asian Screening Array-24 v1.0 Kit (1152 samples)
20016319
The Asian Screening Array is a universal, whole genome array for highly economical genetic risk screening. Each Kit contains 48 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 1152 DNA samples.
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Infinium Asian Screening Array-24+ v1.0 Kit (48 samples)
20016320
The Asian Screening Array is a universal, whole genome array for highly economical genetic risk screening. Each Kit contains 2 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 48 DNA samples.
Infinium Asian Screening Array-24+ v1.0 Kit (288 samples)
20016321
The Asian Screening Array is a universal, whole genome array for highly economical genetic risk screening. Each Kit contains 12 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 288 DNA samples.
Infinium Asian Screening Array-24+ v1.0 Kit (1152 samples)
20016322
The Asian Screening Array is a universal, whole genome array for highly economical genetic risk screening. Each Kit contains 48 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 1152 DNA samples.
Infinium FFPE QC Kit (384 reactions)
WG-321-1001
Infinium FFPE QC Kit is an accessory product required to qualify FFPE samples with Nextera Flex for Enrichment. Library prep, enrichment, enrichment probe panel, and index adapter reagents need to be ordered separately.
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Infinium HD FFPE DNA Restore Kit (24 samples)
WG-321-1002
Contains a combination of novel reagents that are used to restore damaged FFPE DNA. Restored DNA can be genotyped using Illumina FFPE enabled Infinium BeadChips to achieve quality data. The Infinium FFPE Restore Kit is supplied with enough reagents to restore 24 FFPE DNA samples.
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