Human Consortia

Contains about 50,000 SNPs fine-mapping content derived from exome sequencing and meta-analysis of phenotype-specific consortia to drive clinical research of the following traits:

• Psychiatric
• Neurological
• Cancerous
• Cardiometabolic
• Autoimmune
• Anthropometric

Available as add-on content to:

• Infinium Global Screening Array-24+
• Infinium Asian Screening Array-24+

The Multi-Disease Booster may combine with other boosters or base content. Contact your Sales Rep for more information.

Features about 30,000 markers from the Infinium PsychArray-24 BeadChip associated with common psychiatric disorders to inspire psychiatric research including:

• Schizophrenia
• Bipolar disorder
• Autism spectrum disorders
• Attention deficit hyperactivity disorder
• Major depressive disorders
• Obsessive compulsive disorder
• Anorexia
• Tourette's syndrome

Available as add-on content to:

• Infinium Global Screening Array-24+

The Psych Booster may combine with other boosters or base content. Contact your Sales Rep for more information.

Contains 28,000 SNPs curated content focused on a wellness and lifestyle, direct-to-consumer (DTC) application contributed by a consortium of DTC customers

Available as add-on content to:

• Infinium Global Screening Array-24+

The Direct-To-Consumer Booster may combine with other boosters or base content. Contact your Sales Rep for more information.

Features about 75,000 SNPs neurodegenerative diseases-concentrated booster to enable rigorous genetic investigation of monogenic cases of Parkinson’s Disease. The Neuro Booster is an update of the NeuroChip Consortium contributed by a consortium led by National Institute of Aging for the Global Parkinson’s Genetics Program. It will enable discovery, fine mapping, polygenic risk score analysis, and replication of previously identified genetic variants associated with common neurodegenerative diseases including:

• Alzheimer’s Disease
• Parkinson’s Disease
• Amyotrophic Lateral Sclerosis (ALS)
• Multiple Sclerosis (MS)
• Progressive Supranuclear Palsy (PSP)/Corticobasal degeneration (CBD)
• Multiple System Atrophy (MSA)
• Frontotemporal Dementia (FTD)
• Dementia with Lewy Bodies (DLB)

Learn more about Global Parkinson’s Genetics Program: https://parkinsonsroadmap.org/gp2/

Available as add-on content to:

• Infinium Global Diversity Array+

Contact your Sales Rep for more information.

Features over 90,000 SNPs for studying breast cancer in women and men of multiple ancestries. The Confluence Booster will enable discovery of variants for breast cancer risk overall and by subtype, develop multi-ancestry polygenic risk scores for personalized risk assessment and uncover variants for breast cancer survival, pharmacogenomics, and second cancers. The content is carefully selected by National Cancer Institute by leveraging experience with polygenic risk scores for predicting breast cancer across different ancestry groups and subtypes. The Confluence Booster includes:

• Novel variants and highly penetrant mutations identified in CARRIERS, BRIDGES, PERSPECTIVE I&I, BRA-STRAP, AABCGS and ENIGMA
• Known pathogenic variants in breast cancer genes such as BRCA1, BRCA2, ATM, PALB2 and CHEK2.

Learn more about the Confluence project: https://dceg.cancer.gov/research/cancer-types/breast-cancer/confluence-project

Available as add-on content to:

• Infinium Global Screening Array-24+
• Infinium Global Diversity Array-8+

Contact your Sales Rep for more information.

Features pan-ethnic coverage sequence, structural variants of >300 autosomal, X-linked recessive diseases with high detection rates and low residual risk, including:

• Spinal Muscular Atrophy
• Duchenne Muscular Dystrophy
• Cystic Fibrosis
• Hemoglobinopathies
• Fragile X (requires separate assay)

End-to-end solution available through partnership with Igentify for interpretation.

Available as add-on content to:

• Infinium Global Diversity Array-8+

The third-party analysis may not be available in some regions. Contact your Sales Rep for more information.