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Infinium ImmunoArray-24 v2 Kit | Autoimmune disorders content

Infinium ImmunoArray-24 v2 BeadChip Kit

The Infinium ImmunoArray-24 v2 BeadChip is the next-generation genotyping array for detecting genetic variation in the immune system.

5760

Sample throughput

Fixed markers: ~253,702

Number of markers

See full details in the specifications table

Overview

The Infinium ImmunoArray-24 v2 BeadChip is the next-generation genotyping array for detecting genetic variation in the human immune system. This BeadChip includes the most valuable content from the HumanImmuno v1 BeadChip, supplemented with newly selected content produced by the immunology research community. This new content includes the majority of the loci currently published in the GWAS catalog for major autoimmune and inflammatory disorders1 as well as published ancestry informative markers.

Key features

  • Over 250,000 immune specific markers

  • Over 85,000 new markers

  • Includes most valuable content from HumanImmuno v1 BeadChip

  • Focused on 17 major autoimmune disorders

The Infinium ImmunoArray-24 v2 can be tailored to incorporate up to ~390,000 custom beadtypes. This BeadChip is available as a standalone version as well as an add-on to several standard Illumina genotyping BeadChips.

View manifest (array content) files

Specifications

Assay type Infinium HTS
Automation capability Automated array loader, Liquid handling robot(s)
Input quantity 200 ng DNA
Instruments iScan System
Method High-throughput genotyping array, Targeted genotyping array
Nucleic acid type DNA
Number of markers Fixed markers: ~253,702, Custom marker add-on capacity: Up to 390,000 (with + kit versions)
Sample throughput ~5760 samples per week
Specialized sample types FFPE tissue
Species category Human
Technology Microarray
Variant class Single nucleotide polymorphisms (SNPs), Germline variants, Structural variants, Insertions-deletions (indels), Copy number variants (CNVs)

Required products

Match your chosen kit size to the number of samples you run at a time. Each kit is processed as a single batch and is not designed to be divided across multiple experiments. If you are processing several low-throughput batches, order multiple small kits.

/ Results

Applications

Example workflow

1
Select content
2
Process and scan
3
Track, analyze and report

Related applications and methods

Immunogenomics Research

Gain insight into the immune repertoire, disease mechanisms, and the functional impact of immune-related genetic variation with NGS and array solutions.

Human Consortia

Illumina is facilitating collaborative advances in human disease research with population-scale genome-wide association studies. Find out how to join.

Microarray Data Analysis and Experimental Design

Find microarray data analysis tools and tips to help you to visualize and analyze microarray data and facilitate data analysis for large experiments.

Documentation

Product literature
Support documentation

Infinium ImmunoArray-24 v2 BeadChip Kit (48 samples)

WG-357-1001

The Infinium ImmunoArray-24 v2.0 BeadChip includes the most valuable markers from the Illumina’s original HumanImmuno BeadChip, plus additional content from the leading experts in autoimmune diseases, GWAS catalogue and Illumina’s NextBio database. Each Kit contains 2 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 48 DNA samples.

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Infinium ImmunoArray-24 v2 BeadChip Kit (288 samples)

WG-357-1002

The Infinium ImmunoArray-24 v2.0 BeadChip includes the most valuable markers from the Illumina’s original HumanImmuno BeadChip, plus additional content from the leading experts in autoimmune diseases, GWAS catalogue and Illumina’s NextBio database. Each Kit contains 12 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 288 DNA samples.

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Infinium ImmunoArray-24 v2 BeadChip Kit (1152 samples)

WG-357-1003

The Infinium ImmunoArray-24 v2.0 BeadChip includes the most valuable markers from the Illumina’s original HumanImmuno BeadChip, plus additional content from the leading experts in autoimmune diseases, GWAS catalogue and Illumina’s NextBio database. Each Kit contains 48 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 1152 DNA samples.

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Infinium ImmunoArray-24+ v2 BeadChip Kit (48 samples)

WG-357-1011

The Infinium ImmunoArray-24 v2.0 BeadChip includes the most valuable markers from the original HumanImmuno BeadChip, plus additional content from the leading experts in autoimmune diseases, GWAS catalogue, NextBio database, and up to 450K user-defined markers. Each Kit contains 2 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 48 DNA samples.

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Infinium ImmunoArray-24+ v2 BeadChip Kit (288 samples)

WG-357-1012

The Infinium ImmunoArray-24 v2.0 BeadChip includes the most valuable markers from the original HumanImmuno BeadChip, plus additional content from the leading experts in autoimmune diseases, GWAS catalogue, NextBio database, and up to 450K user-defined markers. Each Kit contains 12 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 288 DNA samples.

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Infinium ImmunoArray-24+ v2 BeadChip Kit (1152 samples)

WG-357-1013

The Infinium ImmunoArray-24 v2.0 BeadChip includes the most valuable markers from the original HumanImmuno BeadChip, plus additional content from the leading experts in autoimmune diseases, GWAS catalogue, NextBio database, and up to 450K user-defined markers. Each Kit contains 48 BeadChips, along with reagents for amplifying, fragmenting, hybridizing, labeling and detecting 1152 DNA samples.

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References

1.  https://www.genome.gov/26525384

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