Illumina Protein Prep: A New Standard for Scalable NGS-Based Proteomics

April 7, 2026

Fiona Kaper, PhD, VP and Head of Assay Research & Development at Illumina, presents Illumina’s vision for scalable, accessible, and reliable proteomics as a foundational pillar of multi omics research. Dr. Kaper introduces Illumina Protein Prep, a unified, NGS based proteomics solution that combines SOMAmer based affinity capture with Illumina sequencing, software, and AI driven analysis. The presentation highlights the assay’s coverage of more than 9,500 human protein targets, femtomolar sensitivity, wide dynamic range, and market leading reproducibility. She also details the end to end workflow from automated assay processing through secondary and tertiary analysis and demonstrates how proteomic data can be seamlessly integrated with other omics data using Illumina’s Connected Multiomics platform. Early access studies, including large scale population and rare disease research, show how Illumina Protein Prep enables high confidence biomarker discovery and drug target identification at scale while complementing mass spectrometry workflows. This presentation was delivered as part of the HUPO – Illumina Lunch Symposium at the HUPO World Congress on November 10th, 2025. Learn more about Illumina Protein Prep here: https://www.illumina.com/products/by-... Learn how proteomics as part of a multiomics workflow can boost discovery power: https://www.illumina.com/techniques/m... Subscribe to the Illumina video channel http://www.youtube.com/subscription_center?add_user=IlluminaInc A global genomics leader, Illumina provides comprehensive next-generation sequencing solutions to the research, clinical, and applied markets. Through collaborative innovation, Illumina is fueling groundbreaking advancements in oncology, reproductive health, genetic disease, microbiology, agriculture, forensic science, and beyond. View customer spotlight videos https://www.youtube.com/playlist?list=PLKRu7cmBQlajfheLzgbI4S7xBn7IDbt79 View Illumina webinars https://www.youtube.com/playlist?list=PLKRu7cmBQlahpXlnrrXlQw9itVJ8yHwUZ View Illumina support videos https://www.youtube.com/playlist?list=PLKRu7cmBQlajbm2KGsICWb-JOnusJfYvM LinkedIn: https://www.linkedin.com/company/illumina X: https://x.com/illumina Instagram: https://www.instagram.com/illuminainc/ Facebook: https://www.facebook.com/illuminainc TikTok: https://www.tiktok.com/@illuminainc #illumina #proteomics #HUPOWorldCongress #MassSpectrometry #BiomarkerDiscovery #DrugDiscovery

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