Instruments

NextSeq 550Dx Instrument products and services

Kits, services, and software solutions

Regulated products for IVD assay diagnostics, development, and clinical research

NextSeq 550 reagents

Featured IVD products (in Dx Mode)

NextSeq 550Dx Reagents

These sequencing reagent kits offer a simplified workflow and high data quality for in vitro diagnostic testing on the NextSeq550 Dx Instrument.

Featured clinical research products (in RUO Mode)

TruSight Tumor 170

Comprehensive next-generation sequencing (NGS) assay that targets DNA and RNA variants from the same FFPE sample.

TruSight One Sequencing Panels

Comprehensive sequencing research panels targeting disease-associated regions of the exome with high analytical sensitivity and specificity.

Pillar® oncoReveal™ Myeloid Panel

A 58-gene pan-cancer panel with combined DNA content, utilizing the single-tube SLIMamp™ workflow for fast library prep and turnaround time.

TruSight Oncology 500

Enable CGP with a large pan-cancer panel covering all major variant classes plus gene signatures (TMB, MSI, and HRD) from FFPE tissue.

View all NextSeq 550Dx Instrument products (in RUO Mode)

Automation options

High-throughput library prep automation

Automation methods for many of our library prep assays are available from leading automation companies. Our partners offer a range of automation platforms to address your lab's throughput needs.

Laboratory information management systems (LIMS)

Use a LIMS to automate workflows, track reagents and lots, integrate instruments, and manage samples and associated information.

Featured software solutions (in Dx Mode)

Local Run Manager

An integrated on-instrument software for creating sequencing runs, monitoring run status, and analyzing data (for diagnostic mode only). If your NextSeq 550Dx instrument requires installation of an application to run on the Local Run Manager (LRM), please contact your local sales team to arrange installation.

laptop displaying BaseSpace home page

Illumina Run Manager*

Illumina Run Manager (for diagnostic mode only) on the Illumina DRAGEN Server for NextSeq 550Dx Instruments enables user-friendly sequencing run setup and secondary data analysis to variant call format (VCF).

*Available only in select countries.

More software and informatics solutions (in RUO Mode)

BaseSpace Sequence Hub

The Illumina genomics cloud-computing environment for NGS data analysis and management.

laptop displaying BaseSpace home page

Correlation Engine

Interactive omics knowledge base that puts private omics data in biological context with highly curated public data.

View all software and informatics

Instrument services and training

Instrument performance service

Illumina Proactive is a secure and remote instrument performance and support service. Our field support team can identify risks before your run, perform reagent lot tracking, maximize uptime, and improve lab efficiency.

Instrument qualification services

Our team can help you stay on top of ever-changing standards and regulations. We’ll help your lab meet and maintain compliance requirements with installation, operational, and performance qualification services.

Illumina training

We offer flexible and customizable next-generation sequencing training opportunities, from hands-on training at your lab to online courses and webinars.

View all instrument services

Intended Use for the NextSeq 550Dx Instrument

United States:

The NextSeq 550Dx instrument is intended for targeted sequencing of DNA libraries from human genomic DNA extracted from peripheral whole blood or formalin-fixed, paraffin-embedded (FFPE) tissue when used with in vitro (IVD) diagnostic assays. The NextSeq 550Dx instrument is not intended for whole genome or de novo sequencing. The NextSeq 550Dx instrument is to be used with specific registered, certified, or approved in vitro diagnostic reagents and analytical software.

European Union:

The NextSeq 550Dx instrument is intended for sequencing of DNA libraries when used with in vitro diagnostic assays. The NextSeq 550Dx instrument is to be used with specific registered, certified, or approved in vitro diagnostic reagents and analytical software.