DRAGEN ORA (formerly Enancio's Lena) lossless genomic data compression is now available on-instrument with the NextSeq 1000/2000 Sequencing System and also on the DRAGEN server v3.8.
Learn More About NextSeq 1000/20000Illumina is committed to delivering innovative sequencing technologies, and to helping customers manage growing volumes of data output that result from the proliferation of sequencing-based research. Genomic data compression technology from Enancio, now known as DRAGEN ORA (original read archive) compression, offers optimal levels of speed and efficiency, and nicely complements other Illumina informatics solutions.
Genomic data compression allows for:
Enancio’s lossless genomic data compression technology reduces the data storage footprint by as much as five times by compressing the output from Illumina sequencers. Enancio technology uses a reference-based compression method. The idea is to use an ultra-fast mapping scheme to map reads onto a reference genome, and then store only the data needed to regenerate those reads: a position and a list of differences.
Other data compression technologies usually suffer from low speed. Enancio technology is optimized for high compression ratios, as well as fast compression and decompression rates, while preserving data integrity. Quality scores are encoded in a lossless way using a range encoder and context models adapted to the different types of quality schemes.
All files compressed with the Illumina compression technology can easily be decompressed using our decompression software. The decompression software is free to download and use.
Download NowOnce installed, a simple command can be used to directly pipe the output of decompression on the fly into a wide range of popular mapping tools such as BWA, STAR, and Bowtie. The compression and decompression technology is also being seamlessly integrated within the DRAGEN Bio-It Platform, which provides accurate, ultra-rapid analysis of sequencing data.
Contact us to learn more.
Lynn Fink of Xing Cancer Care discusses how her ISO15189-accredited pathology lab uses Illumina informatics platforms for data analysis and shares why the lab chose these solutions over other options.
View WebinarSecurely store, process, and share large genomic and NGS datasets in the cloud with built-in speed and scalability.
Our sequencing data analysis software helps you spend more time doing research, and less time configuring and running analysis workflows.
Explore a broad range of informatics products designed to simplify genomic data analysis and management.