NextSeq 550Dx Instrument applications and methods

Supporting IVD testing and clinical research

Perform and develop diagnostic assays and fuel clinical research applications with sequencing and array scanning on one instrument

NovaSeq 550Dx flow cell

Key diagnostic applications

When used in diagnostic mode on the NextSeq 550Dx, Illumina DNA Prep with Enrichment Dx supports user-supplied probe panels that meet the required specifications, including fixed and custom panels of varying sizes.

1
Library prep
2
Sequence
3
Analyze

Key clinical research applications (in Research Mode)

The TruSight Tumor 170 workflow covers 170 genes associated with common solid tumors. It simultaneously analyzes DNA and RNA, covering a wide range of genes and variant types.

Read interview

1
Prep
2
Sequence
3
Analyze

Intended Use for the NextSeq 550Dx Instrument

United States:

The NextSeq 550Dx Instrument is intended for targeted sequencing of DNA libraries from human genomic DNA extracted from peripheral whole blood or formalin-fixed, paraffin-embedded (FFPE) tissue when used with in vitro (IVD) diagnostic assays. The NextSeq 550Dx Instrument is not intended for whole genome or de novo sequencing. The NextSeq 550Dx Instrument is to be used with specific registered, certified, or approved in vitro diagnostic reagents and analytical software.

European Union:

The NextSeq 550Dx instrument is intended for sequencing of DNA libraries when used with in vitro diagnostic assays. The NextSeq 550Dx instrument is to be used with specific registered, certified, or approved in vitro diagnostic reagents and analytical software.