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NGS for Infectious Diseases

Coronavirus

Genomics in Infectious Diseases

Genomics is transforming modern infectious disease surveillance, expanding our understanding of pathogen evolution, host–pathogen interactions, and antibiotic resistance. In turn, public health professionals are changing the methods they use to research, monitor, and prevent epidemics and pandemics of high-profile infectious diseases such as influenza, tuberculosis, Ebola, and more recently, coronavirus.

Traditional methods of assessing infectious agents include antibody-based testing, real-time PCR, pulsed field gel electrophoresis, and multilocus sequence typing. These methods are typically useful only for a small and defined number of organisms, and data analysis can be subjective. In contrast, next-generation sequencing (NGS) provides a universal, culture-free method for infectious disease surveillance that may be used with viruses, bacteria, fungi, or parasites, and can replace the need for multiple tests.

Track Emergence & Prevalence of Novel SARS-CoV-2 Strains

COVIDSeq detects the SARS-CoV-2 virus and provides critical information on the epidemiology of new variants.

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How Coronavirus Mutations Can Track Its Spread—and Disprove Conspiracies

Changes in the pathogen help scientists follow cases without widespread testing—and show the virus isn't a bioweapon.

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Molecular Epidemiology

Examine genetic variants that influence disease transmission and prevention, and better understand the mechanisms that lead to infection and spread.

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Featured Infectious Disease Articles

Illumina and IDbyDNA Partner to Deliver NGS Infectious Disease Solutions

The partnership aims to accelerate and improve testing for emerging public health threats like SARS-Cov-2.

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Next-Generation Sequencing Helps Fight Infectious Diseases Globally

NGS technology enabled infectious disease experts to identify and characterize the genome of the novel coronavirus in China.

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Portable iSeq System Used to Characterize Ebola Outbreak

In combination with extensive epidemiological findings, the iSeq 100 System allowed local scientists to analyze transmission patterns and trace the outbreak's origin.

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Accurate Surveillance of Healthcare-Acquired Infections

NGS-based bacterial genome sequencing paired with user-friendly bioMérieux software allows comprehensive isolate discrimination and characterization.

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Featured Infectious Disease Products

Illumina RNA Prep with Enrichment

Achieve rapid, targeted interrogation of an expansive number of target genes with exceptional capture efficiency and coverage uniformity.

MiniSeq Reagent Kits

Access cost-efficient sequencing, even for low numbers of samples.

iSeq System

The iSeq 100 System makes next-generation sequencing easier and more affordable than ever. Labs of all sizes can now easily sequence small genomes, interrogate gene sets, analyze gene expression, and more.

MiniSeq System

The MiniSeq System offers a simple, affordable solution. Advance your research with the power and reliability of proven Illumina NGS technology.

MiSeq System

With the MiSeq System you can access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more.

NextSeq System and Reagents

The NextSeq System provides the flexible power you need for whole-exome, transcriptome, and targeted resequencing.

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