With targeted resequencing, a subset of genes or regions of the genome are isolated and sequenced. Targeted approaches using next-generation sequencing (NGS) allow researchers to focus time, expenses, and data analysis on specific areas of interest. Such targeted analysis can include the exome (the protein-coding portion of the genome), specific genes of interest (custom content), targets within genes, or mitochondrial DNA.
Compared to broader approaches, such as whole-genome sequencing, targeted sequencing is a more cost-effective method for investigating areas of interest. Targeted resequencing enables researchers to focus on regions that are most likely to be involved in the phenotype under study, conserving resources and generating a smaller, more manageable data set. Targeted approaches can also deliver much higher coverage levels, allowing identification of variants that are rare and more expensive with whole-genome or Sanger sequencing.
Find out how targeted sequencing can help you discover more.
Explore common targeted NGS methods, from exome to amplicon sequencing and more.
Discover, validate, or screen genetic variants with targeted sequencing for various research areas, from cancer to microbiology and more.
Explore uses of targeted NGSThis online tool makes it easy to optimize for target region coverage.
Create custom targeted sequencing panels optimized for content of interest.
Rapidly prepare amplicon libraries for Illumina sequencers.
Affordable, fast, and accessible sequencing power for targeted or small genome sequencing in any lab.
Supports a broad range of targeted DNA and RNA applications.
An on-premises software solution for creating sequencing runs, monitoring run status, and analyzing data.
Provides streamlined variant detection of amplicon panels.
NGS supports effective genomic surveillance strategies to reduce infectious disease transmission. Targeted sequencing can be used to monitor zoonotic or respiratory pathogens.
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