Details

The webcast will discuss how genome sequencing and omics approaches are paving the way for precision cardiovascular medicine.

Cardiovascular disease can take many forms, and research projects are identifying a prominent role for genetics. Inherited single-gene mutations are the cause of several monogenic cardiac disorders, and collections of smaller-effect genetic variants are being leveraged to define ‘polygenic risk scores’ for cardiac health. It is therefore becoming increasingly clear that genome sequencing for identifying the underlying genomic basis of a person’s heart health enables personalized monitoring or therapeutic interventions. Thus, the implementation of genome sequencing in healthcare provides a powerful route to precision cardiac medicine.

Beyond the genomics of cardiovascular disease, diverse types of enabling omics technologies — such as epigenomics, metabolomics, and single-cell transcriptomics — are providing detailed molecular and cellular insights into cardiac disorders. Such omics studies can reveal vital mechanistic links between the underlying genetic architecture and healthcare outcomes. These multi-layered insights not only provide a more detailed biological understanding of cardiovascular disorders but also can pinpoint causal pathological mechanisms for therapeutic targeting.

The webcast will consist of presentations from two leading researchers, followed by a question and answer session. Registrants can submit questions live during the webcast for answering by our experts.

Speakers
Victoria Parikh

Dr. Victoria Parikh
Assistant Professor of Medicine (Cardiovascular Medicine)
Stanford University

Muredach Reilly

Dr. Muredach Reilly
Director, Irving Institute for Clinical and Translational Research
Columbia University Department of Medicine

Darren Burgess

Moderator: Dr. Darren Burgess
Senior Editor
Nature Reviews Genetics

M-AMR-00837
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Date & Time
26 Apr. 2022
08:00 AM
Location
North America
Affiliation
Nature Reviews Genetics
Presenter
Dr. Victoria Parikh, Dr. Muredach Reilly; Moderator: Dr. Darren Burgess
Topic
Precision health
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