An important customer notification was announced to a select group of LRM users on May 3, 2022. Please refer to the notification for essential action items or reach out to techsupport@illumina.com. For more information on how Illumina is addressing cybersecurity, read our full announcement here.
Local Run Manager Software
Automatic Data Analysis
Local Run Manager (LRM) software is an integrated solution designed to create sequencing runs, monitor run status, analyze sequencing data, and view results. LRM software integrates with the instrument control software and can be directly accessed on the MiniSeq and iSeq 100 platforms through a web browser. An off-instrument version of the same easy-to-use LRM software is available and compatible with the iSeq System, the MiniSeq System, the MiSeq Series, and the NextSeq 550 Series.
Various optional software modules are available to perform analysis procedures designed for different library types. The LRM software currently works with the analysis software modules listed below.
Find Compatible Library Prep Kits
Most Local Run Manager analysis modules will prompt you to select a library prep kit for a given run. Find out which kits are compatible with each Local Run Manager software analysis module.
Result count: 11
systems
Available Analysis Modules
TruSight Tumor 15 Analysis Module
Analyzes and generates a filtered report for samples prepared using the TruSightTumor 15 assay for 15 genes associated with solid tumors.
View sample dataTruSight Tumor 15 Analysis Module
Small RNA Analysis Module
Aligns reads and outputs hits. Performs optional novel precursor discovery and pairwise differential expression analysis.
View sample dataSmall RNA Analysis Module
RNA Fusion Analysis Module
Aligns reads and detects fusions for RNA libraries prepared with the TruSight RNA Fusion Panel kit.
View sample dataRNA Fusion Analysis Module
Resequencing Analysis Module
Aligns reads and performs variant analysis for whole-genome sequencing of small genomes.
View sample dataResequencing Analysis Module
DNA Enrichment Analysis Module
Aligns reads against a whole genome reference and performs variant analysis for specified regions of interest.
View sample dataDNA Enrichment Analysis Module
Targeted RNA Module
Enables streamlined differential expression analysis of TruSeq Targeted RNA panels sequenced on Illumina sequencing systems.
View sample dataTargeted RNA Module
GenerateFASTQ Analysis Module
Generates demultiplexed FASTQ files for further downstream analysis.
View sample dataGenerateFASTQ Analysis Module
DNA Amplicon Analysis Module
Enables streamlined variant detection of AmpliSeq for Illumina DNA and TruSeq Amplicon panels sequenced on Illumina sequencing systems.
View sample dataDNA Amplicon Analysis Module
Amplicon Module
Enables streamlined variant detection of TruSeq Amplicon panels sequenced on Illumina sequencing systems.
View sample dataAmplicon Module
Amplicon DS Analysis Module
Enables streamlined analysis of the Illumina TruSight Tumor 26 and dual pool (dual strand) TruSeq Custom Amplicon panels.
View sample dataAmplicon DS Analysis Module
RNA Amplicon Analysis Module
Enables streamlined differential expression analysis of AmpliSeq for Illumina RNA targeted panels sequenced on Illumina sequencing systems.
View sample dataRNA Amplicon Analysis Module
Technical Support Bulletins
Technical support bulletins contain details about common procedures and answers to frequently asked questions. See the following bulletins for more information about using Local Run Manager.
Download Analysis Modules or Get Support
Download a specific analysis software module of interest, or access Local Run Manager technical support information.
Download Local Run Manager ModulesAccess Local Run Manager Support