Genomics is transforming modern infectious disease surveillance, expanding our understanding of pathogen evolution, host–pathogen interactions, and antibiotic resistance. In turn, public health professionals are changing the methods they use to research, monitor, and prevent epidemics and pandemics of high-profile infectious diseases such as Influenza, tuberculosis, Ebola, and more recently, coronavirus.
Traditional methods of assessing infectious agents include antibody-based testing, real-time PCR, pulsed field gel electrophoresis (PFGE), and multilocus sequence typing (MLST). These methods are typically useful only for a small and defined number of organisms, and data analysis can be subjective.
The severe acute respiratory syndrome coronavirus COVID-19 outbreak is an important reminder that the global community must strengthen national and international programs for early detection and response to future disease outbreaks.
Illumina's technology was used as part of front line testing to identify coronavirus. We have made our technology available globally to support applications and strategies to improve detection and to enhance our tracking of the epidemiology, evolution, and virulence of COVID-19.Read Article
Effective detection of Coronavirus using a comprehensive targeted enrichment workflow.Read Application Note
A shotgun metagenomics sequencing workflow for effective detection and characterization of coronavirus strains.Read Application Note
The partnership aims to accelerate and improve testing for emerging public health threats like SARS-Cov-2.Read More
NGS technology enabled infectious disease experts to identify and characterize the genome of the novel coronavirus in China.Read Review
This detailed viral information is enabling public health officials to respond with unprecedented speed and breadth.Read Interview
This summary highlights recent peer-reviewed publications in which researchers used NGS to analyze viral populations, microbial pathogenesis, zoonotic reservoirs, the gut microbiome, and more.Read Review
Next-generation sequencing (NGS) provides a universal, hypothesis-free method for infectious disease surveillance that can be used with viruses, bacteria, or parasites. Genomic analysis with NGS provides high-resolution information to distinguish pathogen strains that differ by as little as one single-nucleotide polymorphism (SNP), and it can replace the need for multiple tests.
Illumina NGS technology delivers rapid results and high-quality data that public health professionals are adopting to identify, track, and respond to infectious disease outbreaks.