Complex Disease Large-Scale Genomics
Researchers are harnessing the power of array and NGS technologies to conduct large-scale, global genetic analyses of complex diseases. This high-throughput genomic research is focused on multifactorial genetic discovery of markers related to disease risk. These studies look for changes in structural variation, single nucleotide polymorphisms (SNPs), indels, splice variants, methylation markers.
High-throughput genomic studies with tens to hundreds of thousands of samples require fast, cost-effective array and sequencing tools. Illumina offers array and NGS technologies with unprecedented sample-to-analysis solutions and unparalleled collaborative expertise to meet these needs.
High-Throughput Genomics in Biobanking
Learn how the HUNT Biobank used Illumina high-throughput arrays to identify a gene that protects against heart attacks.
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Polygenic Risk Scores Could Give Physicians New Tools for Diagnosis and Treatment
Researchers perform genome-wide association studies to identify disease-associated DNA risk loci and develop scores for clinical validation.
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Featured High-Throughput Genomics Solutions
HiSeq 4000 System
This dual-flow cell sequencing system delivers the highest throughput and lowest price per sample across multiple applications.
Learn MoreNovaSeq 6000 System
Scalable throughput and flexibility for virtually any genome, sequencing method, and scale of project.
Learn MoreHigh-Throughput Library Prep Automation
For labs preparing large quantities of NGS libraries, liquid-handling robots and other automation solutions provide a good option.
Learn MoreLarge-Scale Sequencing Products
Illumina Advantage large-scale sequencing products offer the highest level of service and support to ensure operational success for clinical research laboratories.
Learn MorePopulation Genomics
National population genomics programs seek to integrate large, diverse data sets, combining clinical information with genomic data at scale in a learning health system.
Learn MoreArray-Based Human Genotyping
Find arrays that make cost-effective, large-scale genotyping studies possible.
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Additional Resources
Driving IBD Discovery with Integrative Genomics
Dr Carl Anderson discusses integrated genomic research approaches in inflammatory bowel disease (IBD) research.
Genomic Architecture of Neurodegenerative Disease
High-throughput genomics enables insights about genes and biological pathways associated with diseases like Alzheimer's and Parkinson's.
The Functional Effects of Genetic Variants
Tuuli Lappalainen, PhD is working toward identifying how genetic differences may affect an individual's risk for certain diseases.
Driving ALS Discovery with Integrative Genomics
Jay Veldink, PhD shares how integrative genomics helped drive his ALS research, leading to the discovery that NEK1 is an ALS gene.
Shared Vision for the Power of Human WGS
Genomics leaders share their perspective on the impact of high-throughput and population sequencing in clinical research.
Chan Zuckerberg Biohub and the NovaSeq System
The Chan Zuckerberg Biohub uses the NovaSeq System to conduct innovative experiments in genomics.
High-Throughput Detection of Somatic Mosaicism
Targeted resequencing is enabling a systematic high-throughput approach to identify rare mosaic mutations in brain malformations.
Untangling Alzheimer's Secrets
Amanda Myers, PhD uses a combination of genomics, transcriptomics, and proteomics to explain the complexity of Alzheimer’s disease.